drugset / Trial / NCT06616532

PM8002 in Combination With Paclitaxel Compared With Chemotherapy as Second-line Treatment in Small Cell Lung Cancer

NCT06616532

Phase 3 Active not recruiting 404 enrolled BioNTech SE
RandomizedParallel-groupOpen-labelTreatment

Summary

PM8002 is a bispecific antibody targeting PD-L1 and VEGF. This study will evaluate the efficacy and safety of PM8002 in combination with Paclitaxel as second-line treatment for SCLC

Timeline

Start
2024-11-13
Primary completion
2027-01-25
Completion
2028-12-25

Drugs

EvaluationDrugModalityDoseRoute
Subject Paclitaxel Small molecule 175 mg/m2 Intravenous
Subject Pumitamig Protein / enzyme biologic Intravenous
Comparator Topotecan Small molecule 1.25 mg/m2 Intravenous