Efficacy of Intravenous Nefopam, Dexmedetomidine, and Meperidine in Preventing Post-Spinal Anesthesia Shivering in Adult Patients Undergoing Lower Abdominal and Lower Limb Surgeries.

Summary

This prospective, randomized, controlled, double-blinded study is designed to evaluate the efficacy of nefopam compared to dexmedetomidine and meperidine for the prevention of postspinal anesthesia shivering while minimizing side effects.

Timeline

Start

2025-01-10

Primary completion

2025-06-30

Completion

2025-07-05

Publications

• Abdelhafez EM, El-Siory W, Turki D, Eissa AA. Efficacy of Intravenous Nefopam, Dexmedetomidine, and Meperidine in Preventing Postspinal Anesthesia Shivering in Adult Patients Undergoing Lower Abdominal and Lower Limb Surgeries: A Double-Blind Comparative Study. Anesthesiol Res Pract. 2025 Dec 3;2025:4549345. doi: 10.1155/anrp/4549345. eCollection 2025.

Drugs

Indications