drugset / Trial / NCT06719544

A Study of Lithium and Enlicitide in Healthy Adult Participants (MK-0616-034)

NCT06719544

Phase 1 Completed 16 enrolled Merck Sharp & Dohme LLC
Non-randomizedCrossoverOpen-labelBasic science

Summary

Researchers have designed a new study medicine called enlicitide decanoate (MK-0616) as a new way to lower the amount of low-density lipoprotein cholesterol (LDL-C) in a person's blood. Enlicitide decanoate will be called "enlicitide" from this point forward. Lithium (also called lithium carbonate) is a medicine used in bipolar disorder. Researchers want to learn about lithium when taken at the same time with enlicitide. They want to: * Measure a person's blood to find out if the amount of lithium in the blood is the same when lithium is taken alone or with enlicitide * Learn about the safety of lithium when taken alone or with enlicitide and if people tolerate it

Timeline

Start
2025-01-02
Primary completion
2025-01-27
Completion
2025-02-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Enlicitide Unknown Oral
Subject Lithium Carbonate Unknown Oral

Indications

No indication recorded.