drugset / Trial / NCT06722521
GUIDE-CAC: Statin-Ezetimibe Without Aspirin vs. Statin Monotherapy With Aspirin in High Coronary Calcification
RandomizedParallel-groupOpen-labelTreatment
Summary
A Multicenter, randomized trial comparing the efficacy and safety of intensive lipid-lowering therapy using a statin-ezetimibe combination without aspirin versus statin monotherapy with aspirin in asymptomatic patients with coronary artery calcification
Timeline
- Start
- 2025-07-09
- Primary completion
- 2032-06-30
- Completion
- 2032-10-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Aspirin | Small molecule | 100 mg | — |
| Subject | Ezetimibe | Unknown | 10 mg | — |
| Comparator | Pitavastatin | Small molecule | 2 mg | — |
| Comparator | Pitavastatin | Small molecule | 4 mg | — |