drugset / Trial / NCT06729970
A Study to Evaluate the Effects of Lithium, Valproic Acid, and Lamotrigine on the Pharmacokinetics of KarXT and Effects of KarXT on the Pharmacokinetics of Lithium, Valproic Acid, and Lamotrigine in Healthy Participants
Non-randomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to evaluate the effects of lithium, valproic acid, and lamotrigine on the single-dose pharmacokinetics (PK) of KarXT and the effect of KarXT on the single-dose PK of lithium, valproic acid, and lamotrigine in healthy participants.
Timeline
- Start
- 2024-12-26
- Primary completion
- 2026-01-23
- Completion
- 2026-01-23
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lamotrigine | Small molecule | — | — |
| Subject | Lithium | Unknown | — | — |
| Subject | Valproic Acid | Small molecule | — | — |
| Subject | Xanomeline/Trospium Chloride | Unknown | — | — |
Indications
No indication recorded.