drugset / Trial / NCT06738251

A Phase III Study of SHR-A2102 Versus Investigator-selected Therapy in Advanced Urothelial Carcinoma

NCT06738251

Phase 3 Recruiting 402 enrolled Shanghai Hengrui Pharmaceutical Co., Ltd.
RandomizedParallel-groupOpen-labelTreatment

Summary

To evaluate the efficacy and safety of SHR-A2102 for injection versus Investigator-selected Therapy in patients with Locally advanced or Metastatic Urothelial Carcinoma who have been previously treated with platinum-based chemotherapy and PD-(L)1 inhibitors.

Timeline

Start
2025-02-12
Primary completion
2026-07
Completion
2027-09

Drugs

EvaluationDrugModalityDoseRoute
Comparator Docetaxel Small molecule
Comparator Gemcitabine Small molecule
Comparator Paclitaxel Small molecule
Comparator Pemetrexed Small molecule
Subject SHR-A2102 Other / unclassified

Indications