GDM: Insulin with or Without Metformin?

Summary

This will be a randomized trial of patients with gestational diabetes who start hypoglycemic therapy with metformin but eventually require insulin. It will examine whether continuing metformin when adding insulin versus discontinuing metformin when insulin is added is beneficial. The investigators hypothesize that continuing metformin will reduce the needed insulin dosage and improve maternal and neonatal outcomes in these patients.

Timeline

Start

2024-12-12

Primary completion

2026-05-01

Completion

2027-05-01

Drugs

Indications