drugset / Trial / NCT06786689

To Compare the Efficacy of Weekly Azathioprine Pulse Versus Betamethasone Oral Mini-Pulse in the Treatment of Moderate to Severe Alopecia Areata

NCT06786689

Phase 2 Completed 60 enrolled Sheikh Zayed Medical College
RandomizedParallel-groupOpen-labelTreatment

Summary

Alopecia areata (AA) is an autoimmune condition characterized by non-scarring hair loss, ranging from minor patches to complete baldness. Given the variable effectiveness of existing treatments, this study aimed to compare the efficacy of weekly Azathioprine pulse (WAP) therapy against Betamethasone oral mini-pulse (BOMP) therapy in managing moderate to severe AA.

Timeline

Start
2023-03-01
Primary completion
2023-05-31
Completion
2023-09-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Azathioprine Small molecule 300 mg
Comparator Betamethasone Other / unclassified 5 mg Oral

Indications