drugset / Trial / NCT06860100
Dexmedetomidine vs Tramadol for Anxiety, Pain, and Hemodynamics in Hemorrhoidectomy
RandomizedParallel-groupDouble-blindTreatment
Summary
This randomized controlled study aims to evaluate the effects of preoperative dexmedetomidine and tramadol on perioperative anxiety, postoperative pain, sedation, and hemodynamic parameters in patients undergoing hemorrhoidectomy under saddle spinal anesthesia with low-dose hyperbaric bupivacaine. Preoperative anxiety levels will be assessed using the State-Trait Anxiety Inventory (STAI), and postoperative pain will be evaluated using the Visual Analog Scale (VAS) at predefined postoperative time points. Intraoperative hemodynamic parameters, sedation levels, and rescue sedative requirements will also be recorded and compared among the study groups.
Timeline
- Start
- 2025-11-17
- Primary completion
- 2026-06
- Completion
- 2026-09-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexmedetomidine | Other / unclassified | 1 ug/kg | Intravenous |
| Subject | Tramadol | Other / unclassified | 1 mg/kg | Intravenous |