drugset / Trial / NCT06897696
Effect of Dexmedetomidine and Total Intravenous Anesthesia on Endothelial Damage-Related Biomarkers
RandomizedParallel-groupTriple-blindPrevention
Summary
This study aimed to evaluate whether dexmedetomidine has a protective effect on endothelial damage by measuring plasma syndecan1 and heparan sulphate levels in rhinoplasty patients who take propofol+remifentanyl infusion.
Timeline
- Start
- 2025-04-10
- Primary completion
- 2025-10-31
- Completion
- 2025-10-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dexmedetomidine | Other / unclassified | 0.3 ug/kg | — |
| Comparator | Dexmedetomidine | Other / unclassified | 0.5 ug/kg | — |
| Comparator | Propofol | Small molecule | 5 mg/kg | — |
| Comparator | Propofol | Small molecule | 8 mg/kg | — |
| Comparator | Remifentanil | Small molecule | 5 ug/kg | — |
| Comparator | Remifentanil | Small molecule | 10 ug/kg | — |