drugset / Trial / NCT07024173
A Phase 3 Study of HRS-8080 Versus Treatment Chosen by Physicians in Locally Advanced and Metastatic Breast Cancer
RandomizedParallel-groupOpen-labelTreatment
Summary
This study is a multicenter, open-label, randomized controlled Phase 3 clinical trial. It is planned to enroll 240 female patients with locally advanced or metastatic breast cancer followed by disease progression after previous endocrine therapy.
Timeline
- Start
- 2025-07-23
- Primary completion
- 2026-12
- Completion
- 2027-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Anastrozole | Other / unclassified | — | Oral |
| Comparator | Everolimus | Small molecule | — | Oral |
| Comparator | Exemestane | Small molecule | — | Oral |
| Comparator | Fulvestrant | Small molecule | — | Other |
| Subject | HRS-8080 | Unknown | — | Oral |
| Comparator | Letrozole | Other / unclassified | — | Oral |