drugset / Trial / NCT07035392

Adebrelimab + Chemotherapy as Neoadjuvant Therapy for Resectable NSCLC

NCT07035392 ↗

Phase 2 Not yet recruiting 32 enrolled Zhangzhou Municipal Hospital
NaSingle-groupOpen-labelTreatment

Summary

This study is a single arm, prospective, multicenter clinical trial, and eligible patients will receive the following treatment regimen: Adebrelimab combined with chemotherapy.The study includes a screening period (from the signing of informed consent by the subjects to no more than 28 days before the first medication, imaging examinations are allowed to be performed within 28 days before the first medication, and tumor tissue biopsy is allowed to be archived within 6 months before the first medication), a treatment period (including neoadjuvant and surgical treatment), and a follow-up period (including safety follow-up and survival follow-up).

Timeline

Start
2025-06-20
Primary completion
2026-12-01
Completion
2026-12-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Adebrelimab Monoclonal antibody 1200 mg Intravenous
Subject Albumin paclitaxel Unknown 260 mg/m2 Intravenous
Subject Pemetrexed Small molecule 500 mg/m2 Intravenous
Background Carboplatin Small molecule — Intravenous