Ultrasound Guided Fluid Loading Before Spinal Anesthesia

Summary

Perioperative hypotension is a common complication of spinal anesthesia during cesarean sections. The aim of this study was to evaluate the effectiveness of echoguided correction of hypovolemia through crystalloid preloading on the incidence of arterial hypotension during scheduled cesarean sections under spinal anesthesia. It was a double-blind, randomized controlled trial study conducted on hypovolemic parturients, scheduled for cesarean section. investigators compared ultrasound guided correction of hypovolemia to a standard care protocol without preloading. Hypovolemia was defined as a ≥12% increase in the variation of the velocity-time integral of subaortic blood flow during a passive leg raising test. Preloading was guided by the variation of the velocity-time integral of subaortic blood flow during volume expansion tests.

Timeline

Start

2024-05-01

Primary completion

2024-12-01

Completion

2025-03-25

Publications

• Ben Marzouk S, Fouzai B, Dhraief N, Ben Amor F, Hkiri T, Hamdi H, Trablesi S, Kalai A, Maghrebi H. Cardiac ultrasound-guided crystalloid preloading before spinal anesthesia vs. standard coloading for scheduled cesarean delivery: a randomized controlled trial. Int J Obstet Anesth. 2026 May;66:104840. doi: 10.1016/j.ijoa.2025.104840. Epub 2025 Dec 29.

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Indications