drugset / Trial / NCT07138898
Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder Arthroplasty
RandomizedParallel-groupSingle-blindTreatment
Summary
The purpose of this study is to assess the incidence of rheumatologic flares, changes in pain scores (VAS), changes in functional outcomes (PROMIS), wound complications, surgical site infections, and return trips to the operating room for rheumatology patients following shoulder replacements, comparing those who stop their immunosuppressants preoperatively for the same amount of time as suggested in the literature for hip and knee arthroplasty versus those who hold the medications for a shorter period of time preoperatively.
Timeline
- Start
- 2025-12-12
- Primary completion
- 2028-01
- Completion
- 2028-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Abatacept | Other / unclassified | — | — |
| Subject | Adalimumab | Monoclonal antibody | — | — |
| Subject | Anakinra | Protein / enzyme biologic | — | — |
| Subject | Azathioprine | Small molecule | — | — |
| Subject | Belimumab | Monoclonal antibody | — | — |
| Subject | Bimekizumab | Monoclonal antibody | — | — |
| Subject | Canakinumab | Monoclonal antibody | — | — |
| Subject | Certolizumab | Protein / enzyme biologic | — | — |
| Subject | Cyclosporine | Peptide | — | — |
| Subject | Etanercept | Protein / enzyme biologic | — | — |
| Subject | Golimumab | Monoclonal antibody | — | — |
| Subject | Guselkumab | Monoclonal antibody | — | — |
| Subject | Hydroxychloroquine | Small molecule | — | — |
| Subject | Infliximab | Monoclonal antibody | — | — |
| Subject | Ixekizumab | Monoclonal antibody | — | — |
| Subject | Leflunomide | Small molecule | — | — |
| Subject | Methotrexate | Small molecule | — | — |
| Subject | Mycophenolate Sodium | Unknown | — | — |
| Subject | Risankizumab | Monoclonal antibody | — | — |
| Subject | Rituximab | Monoclonal antibody | — | — |
| Subject | Secukinumab | Monoclonal antibody | — | — |
| Subject | Sulfasalazine | Small molecule | — | — |
| Subject | Tacrolimus | Small molecule | — | — |
| Subject | Tocilizumab | Monoclonal antibody | — | — |
| Subject | Tofacitinib | Small molecule | — | — |
| Subject | Upadacitinib | Small molecule | — | — |
| Subject | Ustekinumab | Monoclonal antibody | — | — |