drugset / Trial / NCT07144215
ED50 of Dexmedetomidine as an Adjuvant to 0.5% Hyperbaric Bupivacaine 12.5 mg for Spinal Anesthesia in Hip and Knee Surgery: An Up-and-Down Method Approach
Non-randomizedSequentialTriple-blindTreatment
Summary
Determine ED50 dexmedetomidine adjuvant that can provide spinal anesthetic sensory blockade duration of 200 minutes on knee and pelvis surgery with up-and-down method.
Timeline
- Start
- 2025-02-01
- Primary completion
- 2025-05-31
- Completion
- 2025-05-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexmedetomidine | Other / unclassified | 3 ug | Other |
| Subject | Dexmedetomidine | Other / unclassified | 4 ug | Other |
| Subject | Dexmedetomidine | Other / unclassified | 5 ug | Other |
| Subject | Dexmedetomidine | Other / unclassified | 6 ug | Other |
| Background | Bupivacaine | Other / unclassified | 12.5 mg | Other |
Indications
No indication recorded.