drugset / Trial / NCT07144267
Comparison of Milrinone and Epinephrine on TAPSE
RandomizedParallel-groupDouble-blindTreatment
Summary
Cardiopulmonary bypass (CPB) is a critical technology in cardiac surgery, allowing for the temporary replacement of the heart and lung functions during intricate surgical procedures. it has significant post-surgical complications, the most important complications of CPB is right ventricle (RV) dysfunction. Diagnosis and management of RV dysfunction is crucial for maintenance of hemodynamic stability and organ function in early post-operation period and prognostic for later phase.
Timeline
- Start
- 2026-03-01
- Primary completion
- 2027-12-30
- Completion
- 2028-03-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Epinephrine | Other / unclassified | 0.05 ug/kg | Intravenous |
| Comparator | Epinephrine | Other / unclassified | 0.1 ug/kg | Intravenous |
| Comparator | Milrinone | Small molecule | 0.4 ug/kg | — |
| Comparator | Milrinone | Small molecule | 0.8 ug/kg | — |
Indications
No indication recorded.