drugset / Trial / NCT07165886
Sirolimus for Injection (Albumin Bound) Combined With Octreotide Long-acting Injection in Patients With Metastatic Gastroenteropancreatic Neuroendocrine Tumors
RandomizedParallel-groupOpen-labelTreatment
Summary
There is limited evidence regarding the benefit of adding somatostatin analogs to molecular targeted agents for well-differentiated gastroenteropancreatic neuroendocrine tumors (GEP-NETs) with poor prognostic factors. This trial is conducted to evaluate sirolimus for injection (albumin bound) combined with octreotide long-acting injection in patients with unresectable or recurrent GEP-NETs.
Timeline
- Start
- 2025-08-29
- Primary completion
- 2028-08-29
- Completion
- 2028-08-29
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Everolimus | Small molecule | — | Oral |
| Subject | Octreotide | Peptide | — | — |
| Subject | Sirolimus | Small molecule | — | Intravenous |