drugset / Trial / NCT07165886

Sirolimus for Injection (Albumin Bound) Combined With Octreotide Long-acting Injection in Patients With Metastatic Gastroenteropancreatic Neuroendocrine Tumors

NCT07165886

Phase 2/3 Recruiting 298 enrolled CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
RandomizedParallel-groupOpen-labelTreatment

Summary

There is limited evidence regarding the benefit of adding somatostatin analogs to molecular targeted agents for well-differentiated gastroenteropancreatic neuroendocrine tumors (GEP-NETs) with poor prognostic factors. This trial is conducted to evaluate sirolimus for injection (albumin bound) combined with octreotide long-acting injection in patients with unresectable or recurrent GEP-NETs.

Timeline

Start
2025-08-29
Primary completion
2028-08-29
Completion
2028-08-29

Drugs

EvaluationDrugModalityDoseRoute
Comparator Everolimus Small molecule Oral
Subject Octreotide Peptide
Subject Sirolimus Small molecule Intravenous