drugset / Trial / NCT07234162

A Phase 3 Multinational Study of Golidocitinib Versus Investigator's Choice in r/r PTCL (JACKPOT19)

NCT07234162

Phase 3 Recruiting 218 enrolled Dizal Pharmaceuticals
RandomizedParallel-groupOpen-labelTreatment

Summary

This is a phase 3, open-label, randomized, multinational study to evaluate the anti-tumor efficacy of golidocitinib versus investigator's choice in adult patients with relapsed/refractory peripheral T-cell lymphoma (r/r PTCL). This study will treat patients with pathologically confirmed PTCL who have relapsed after or been refractory/intolerant to at least one prior systemic treatment regimen(s).

Timeline

Start
2024-05-13
Primary completion
2027-11-30
Completion
2028-10-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Gemcitabine Small molecule 1000 mg/m2 Intravenous
Subject Golidocitinib Small molecule 150 mg Oral
Comparator Tucidinostat Small molecule 30 mg Oral