Dose-Finding Study: MEV90 for Local Anesthetic in Interscalene Block for Supraclavicular Nerves Block

Recruiting 55 enrolled Hospital del Trabajador de Santiago

NaSingle-groupOpen-labelSupportive care

Summary

This study aims to determine the minimum effective volume (MEV90) of local anesthetic required to achieve sensory block of the supraclavicular nerves when performing a single-shot ultrasound-guided interscalene brachial plexus block (ISB). These nerves provide sensation to the skin over the clavicle and shoulder and are often involved in surgeries such as shoulder arthroscopy and clavicle repair.

Timeline

Start: 2026-04
Primary completion: 2026-11
Completion: 2026-12

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Bupivacaine	Other / unclassified	12 ml	Other
Subject	Bupivacaine	Other / unclassified	14 ml	Other
Subject	Bupivacaine	Other / unclassified	16 ml	Other
Subject	Bupivacaine	Other / unclassified	18 ml	Other
Subject	Bupivacaine	Other / unclassified	20 ml	Other
Subject	Bupivacaine	Other / unclassified	22 ml	Other
Subject	Bupivacaine	Other / unclassified	24 ml	Other
Subject	Bupivacaine	Other / unclassified	26 ml	Other
Subject	Bupivacaine	Other / unclassified	28 ml	Other
Subject	Bupivacaine	Other / unclassified	30 ml	Other
Background	Epinephrine	Other / unclassified	5 ug/ml	Other

Indications

No indication recorded.