drugset / Trial / NCT07362914
Corticosteroids for Doxorubicin Liposome-Induced Hand-Foot-Skin Reactions
RandomizedParallel-groupOpen-labelTreatment
Summary
Investigating the Association Between Corticosteroid Use and Improvement in Doxorubicin Liposome-Induced Cutaneous Toxicity: Exploring the Feasibility and Mechanisms of Corticosteroids in Mitigating Liposomal Doxorubicin-Related Dermatologic Adverse Effects.
Timeline
- Start
- 2025-03-07
- Primary completion
- 2026-07-30
- Completion
- 2027-01-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexamethasone | Small molecule | 12 mg | Oral |
| Background | Cyclophosphamide | Other / unclassified | 600 mg/m2 | Intravenous |
| Background | Doxorubicin | Other / unclassified | 35 mg/m2 | Intravenous |