drugset / Trial / NCT07365800
The MDK Study: Using a Combination of Methadone-dexmedetomidine-ketamine for Postoperative Pain Control in Patients Undergoing Complex Spine Surgeries.
Non-randomizedParallel-groupOpen-labelTreatment
Summary
This study will investigate whether a combination of three anesthetic medications will reduce intraoperative and postoperative pain in patients undergoing complex spine surgery, and whether it will reduce the use of opioid pain medication after surgery.
Timeline
- Start
- 2026-04-24
- Primary completion
- 2026-12
- Completion
- 2027-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexmedetomidine | Other / unclassified | — | Intravenous |
| Subject | Ketamine | Small molecule | — | Intravenous |
| Subject | Methadone | Other / unclassified | — | Intravenous |