Caudal Dexmedetomidine vs Ketamine for Postoperative Analgesia in Pediatric DDH Surgery

Summary

This study compares two medicines, Dexmedetomidine and Ketamine, added to caudal Bupivacaine to control pain after hip surgery in children. We will check how well each medicine reduces pain, how long the pain relief lasts, and if children need extra pain medicine. The goal is to find the safest and most effective option for postoperative pain relief in children undergoing hip surgery.

Timeline

Start

2026-03-01

Primary completion

2026-08

Completion

2026-09

Publications

• Background Yoon JH, Park J, Conde J, Wakamiya M, Prakash L, Prakash S. Rev1 promotes replication through UV lesions in conjunction with DNA polymerases eta, iota, and kappa but not DNA polymerase zeta. Genes Dev. 2015 Dec 15;29(24):2588-602. doi: 10.1101/gad.272229.115.
• Background Tait AR, Burke C, Voepel-Lewis T, Chiravuri D, Wagner D, Malviya S. Glycopyrrolate does not reduce the incidence of perioperative adverse events in children with upper respiratory tract infections. Anesth Analg. 2007 Feb;104(2):265-70. doi: 10.1213/01.ane.0000243333.96141.40.
• Background Zink W, Graf BM. Local anesthetic myotoxicity. Reg Anesth Pain Med. 2004 Jul-Aug;29(4):333-40. doi: 10.1016/j.rapm.2004.02.008.
• Background Beckie TM, Beckstead JW, Groer MW. The influence of cardiac rehabilitation on inflammation and metabolic syndrome in women with coronary heart disease. J Cardiovasc Nurs. 2010 Jan-Feb;25(1):52-60. doi: 10.1097/JCN.0b013e3181b7e500.
• Background Mokta KK, Kanga AK, Kaushal RK. Neonatal listeriosis: a case report from sub-Himalayas. Indian J Med Microbiol. 2010 Oct-Dec;28(4):385-7. doi: 10.4103/0255-0857.71824.

Drugs

Indications