drugset / Trial / NCT07445334
Catheter Ablation Versus Anti-arrhythmic Drugs for Premature Ventricular Complexes
RandomizedParallel-groupSingle-blindTreatment
Summary
Premature ventricular complexes (PVCs) are extra, abnormal heart beats arising from the ventricles of the heart and are the most common ventricular arrhythmia. PVCs can be treated with medication or with a procedure called catheter ablation. It is not known which provides a better cure or provides better quality of life. The purpose of this research project is to study the best way to treat PVCs by comparing the use of medication to catheter ablation to assess which approach is better at reducing symptoms and improving quality of life.
Timeline
- Start
- 2026-03-01
- Primary completion
- 2027-09-01
- Completion
- 2028-03-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Atenolol | Other / unclassified | — | — |
| Comparator | Bisoprolol | Other / unclassified | — | — |
| Comparator | Carvedilol | Other / unclassified | — | — |
| Comparator | Diltiazem | Small molecule | — | — |
| Comparator | Metoprolol | Other / unclassified | — | — |
| Comparator | Verapamil | Other / unclassified | — | — |
| Comparator | flecainide | Small molecule | — | — |
| Comparator | sotalol | Small molecule | 80 mg | — |