drugset / Trial / NCT07475156
The Effect of Dexmedetomidine Infusion Alone Versus the Combination of Dexmedetomidine and Melatonin on Reduction of Post-operative Delirium (POD) After Open Brain Surgeries
RandomizedParallel-groupTriple-blindPrevention
Summary
The aim of this study is to illuminate the effect of combination of dexmedetomidine and oral melatonin versus the use of dexmedetomidine infusion alone on the improving of post-operative delirium (POD) on patients undergoing open brain surgeries.
Timeline
- Start
- 2025-08-01
- Primary completion
- 2026-01-15
- Completion
- 2026-02-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Melatonin | Small molecule | 3 mg | Oral |
| Comparator | Dexmedetomidine | Other / unclassified | 0.5 ug/kg | Intravenous |