drugset / Trial / NCT07493109

Chidamide for Maintenance Treatment of HBV-infected Diffuse DLBCL in Patients Initially Treated With R-CHOP

NCT07493109

Phase 3 Recruiting 200 enrolled Ou Bai, MD/PHD
RandomizedParallel-groupOpen-labelTreatment

Summary

To evaluate the efficacy and safety of chidamide monotherapy as maintenance treatment in patients with diffuse large B-cell lymphoma (DLBCL) and HBV infection following initial response to R-CHOP therapy, and to provide evidence for the clinical application of chidamide.

Timeline

Start
2026-05-30
Primary completion
2029-09-30
Completion
2030-09-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Tucidinostat Small molecule 20 mg
Comparator Entecavir Small molecule 0.5 mg