Effect of Lidocaine Infusion Versus Dexmedemidine Infusion on the Neurocognitive Function of Elderly Patients Undergoing Endoscopic Retrograde Cholangiopancreatography(ERCP).

Completed 30 enrolled Benha University

RandomizedParallel-groupDouble-blindTreatment

Summary

dexmedetomidine infusion or lidocaine infusion starting before induction of intravenous general anesthesia and continue as infusion intraoperative can reduce postoperative cognitive dysfunction incidence (primary outcome), postoperative cognitive dilirium, postoperative pain, opioid consumption, postoperative inflammatory response and postoperative adverse events (secondary outcomes) in elderly patients undergoing ERCP.

Timeline

Start: 2024-12-23
Primary completion: 2025-04-23
Completion: 2025-08-23

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Dexmedetomidine	Other / unclassified	0.6 ug/kg	Intravenous
Comparator	Lidocaine	Other / unclassified	1.5 mg/kg	Intravenous

Indications

No indication recorded.