Mucoadhesive Gels in Controlling Gag Reflex Among Children During Dental Radiographic Examination

Summary

This randomized clinical trial compares tannic acid-zinc acetate mucoadhesive gel with lidocaine gel for reducing gag reflex in children aged 8-10 years during radiographic dental examination Gag reflex severity and pulse rate will be assessed before and after gel application. The study evaluates the effectiveness of the tested gel as a potential alternative to lidocaine.

Timeline

Start

2026-09-01

Primary completion

2026-10-01

Completion

2026-11-01

Publications

• Background Elbay M, Tak O, Sermet Elbay U, Kaya C, Eryilmaz K. The use of low-level laser therapy for controlling the gag reflex in children during intraoral radiography. Lasers Med Sci. 2016 Feb;31(2):355-61. doi: 10.1007/s10103-016-1869-z. Epub 2016 Jan 11.
• Background Nikkerdar N, Seyedi H, Mirzaeei S, Safari-Faramani R, Golshah A. Comparative effects of three mucoadhesive gels containing lidocaine, zinc acetate, and tannic acid on the gag reflex of dental patients: a randomized double-blind clinical trial. BMC Oral Health. 2024 Nov 27;24(1):1442. doi: 10.1186/s12903-024-05248-9.
• Background Eachempati P, Kumbargere Nagraj S, Kiran Kumar Krishanappa S, George RP, Soe HHK, Karanth L. Management of gag reflex for patients undergoing dental treatment. Cochrane Database Syst Rev. 2019 Nov 13;2019(11):CD011116. doi: 10.1002/14651858.CD011116.pub3.
• Background Bassi GS, Humphris GM, Longman LP. The etiology and management of gagging: a review of the literature. J Prosthet Dent. 2004 May;91(5):459-67. doi: 10.1016/S0022391304000939.

Drugs

Indications

No indication recorded.