drugset / Trial / NCT07525648

Comparison of the Effects of Sevoflurane and Desflurane on Optic Nerve Sheath Diameter During Laparoscopic Surgery

NCT07525648

Completed 63 enrolled Medipol University
RandomizedParallel-groupOpen-labelBasic science

Summary

Laparoscopic surgeries require pneumoperitoneum and Trendelenburg position, which may lead to increased intracranial pressure (ICP). Optic nerve sheath diameter (ONSD) measurement via ultrasound is a non-invasive method to evaluate ICP. This prospective study aims to compare the effects of sevoflurane and desflurane on ONSD in patients undergoing laparoscopic hysterectomy and bilateral oophorectomy in the Trendelenburg position.

Timeline

Start
2026-04-15
Primary completion
2026-05-25
Completion
2026-06-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Desflurane Other / unclassified
Comparator Sevoflurane Other / unclassified