drugset / Trial / NCT07544576

Comparing Treatment of Knee Osteoarthritis With Triamcinolone Injections Using 40mg With Landmark Guidance and 20mg With Ultrasound Guidance

NCT07544576

Phase 4 Enrolling by invitation 140 enrolled Sosi Dzhugarian
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to determine whether a lower dose of corticosteroid injection with ultrasound-guidance for the treatment of knee osteoarthritis can be as effective as a higher dose that is landmark-guided. With landmark-guided dosing, it may be reasonable to use a higher amount of corticosteroid in order to ensure a sufficient amount of the medication is administered, however these injections carry the risk of side effects. Alternatively, with the use of ultrasound, it may be reasonable to use less corticosteroid, possibly decreasing the risk of side effects and increasing patient satisfaction.

Timeline

Start
2025-12-12
Primary completion
2026-12-08
Completion
2026-12-08

Drugs

EvaluationDrugModalityDoseRoute
Comparator Triamcinolone Acetonide Other / unclassified 20 mg Other
Comparator Triamcinolone Acetonide Other / unclassified 40 mg Other
Comparator Lidocaine Other / unclassified 3 ml

Indications