drugset / Trial / NCT07582471

Insulin Versus Oral Hypoglycemic Agents in Gestational Diabetes Mellitus

NCT07582471

Completed 60 enrolled Dr Mudassar Saeed Pansota
RandomizedParallel-groupOpen-labelTreatment

Summary

In order to ascertain the relative safety and effectiveness of insulin and OHAs in the treatment of GDM, well-designed, prospective clinical trials are required. GDM is growing more common, and proper care is crucial to preventing complications. Although the evidence is conflicting, both therapy approaches might be beneficial. To maximize outcomes for both mother and child, evidence-based recommendations for pregnant women with GDM must close this knowledge gap. Comparing the effects of insulin and metformin in gestational diabetes mellitus is the rationale for this study. We can thus give our people a medication with less fetal adverse effects based on these findings. Based on this empirical data, we can then incorporate some useful suggestions into our standard practice guidelines for the use of the more effective medication of the two for gestational diabetes mellitus in order to lower perinatal mortality and fetal morbidity.

Timeline

Start
2025-10-08
Primary completion
2026-04-07
Completion
2026-04-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Insulin Protein / enzyme biologic Subcutaneous
Comparator Metformin Small molecule 500 mg Oral

Indications