Dexmedetomidine vs Lignocaine for Reducing Intubation-Induced Hemodynamic Responses in Cardiac Surgery: A Randomized Controlled Trial

Summary

After confirming eligibility, written informed consent will be obtained by a trained team member who is not involved in assigning treatment or giving the study medication. Each participant will receive a unique study number to protect privacy. Participants will be randomly assigned to receive one of the study medications using a chance-based method.The study medication will be administered through a vein before placement of the breathing tube. Blood pressure and pulse rate will be measured before the procedure and at several time points after the breathing tube is inserted.

Timeline

Start

2026-05-21

Primary completion

2026-08-21

Completion

2026-08-21

Publications

• Background Dube S, Gosavi K, Admane G. Comparative study of Dexmedetomidine, Lignocaine and their combination for the attenuation of hemodynamic response during laryngoscopy and intubation [Internet]. Indian J Clin Anaesth. 2022 [cited 2026 May 21];9(1):27-31. Available from: https://doi.org/10.18231/j.ijca.2022.007

Drugs

Indications

No indication recorded.