drugset / Trial / NCT07642024

A Study of BL-B01D1 in Combination With Osimertinib as Perioperative Therapy in Patients With EGFR-mutated Resectable Non-small Cell Lung Cancer(PANKU-Lung09)

NCT07642024

RandomizedParallel-groupOpen-labelTreatment

Summary

This trial is a registrational Phase II/III, randomized, open-label, multicenter study to evaluate the efficacy and safety of BL-B01D1 in combination with osimertinib in resectable EGFR-mutant non-small cell lung cancer.

Timeline

Start
2026-06
Primary completion
2032-12
Completion
2032-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Carboplatin Small molecule Intravenous
Comparator Cisplatin Other / unclassified Intravenous
Subject Izalontamab Brengitecan Unknown Intravenous
Subject Osimertinib Small molecule Oral
Comparator Pemetrexed Small molecule Intravenous