drugset / Trial / NCT07664592
Comparative Efficacy of Different Dentin Occluding Toothpaste Technologies
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The purpose of this clinical study is to evaluate and compare how well three different types of toothpaste technologies work to relieve tooth sensitivity, also known as dentin hypersensitivity. The study asks the question: How effective are toothpastes containing 8% Arginine, 8% Arginine with Zinc Phosphate, or 5% Calcium Sodium Phosphosilicate (CSPS) at providing immediate and short-term relief for people suffering from sensitive teeth?
Timeline
- Start
- 2026-06-29
- Primary completion
- 2026-07-21
- Completion
- 2026-09-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | L-arginine | Small molecule | 8 % | — |
| Comparator | PHOSPHINE SILANE | Other / unclassified | 5 % | — |
| Subject | Zinc Sulfate | Unknown | — | — |