drugset / Trial / NCT07675291
Rituximab Combining With Low-Dose Mycophenolate Mofetil on Proliferative Lupus Nephritis in Children
RandomizedParallel-groupOpen-labelTreatment
Summary
The objective of this study is to assess the efficacy and safety of rituximab combining with low-dose mycophenolate mofetil in the induction therapy of proliferative lupus nephritis in children.
Timeline
- Start
- 2026-06
- Primary completion
- 2028-12-31
- Completion
- 2028-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cyclophosphamide | Other / unclassified | 750 mg/m2 | — |
| Subject | Mycophenolate Mofetil | Small molecule | 10 mg/kg | — |
| Subject | Mycophenolate Mofetil | Small molecule | 15 mg/kg | — |
| Subject | Rituximab | Monoclonal antibody | 375 mg/m2 | — |
| Background | Hydroxychloroquine | Small molecule | — | — |