drugset / Trial / NCT07707544

Idiopathic Intracranial Hypertension: Prognostic Factors and Multidisciplinary Management

NCT07707544

Active not recruiting 30 enrolled Sohag University
RandomizedSingle-groupOpen-labelTreatment

Summary

Several studies have investigated factors associated with visual deterioration in BIIP patients. Severe papilledema, delayed diagnosis, high CSF opening pressure, obesity, and visual field defects have been associated with poor prognosis. Optical Coherence Tomography has emerged as a valuable tool for monitoring retinal nerve fiber layer changes and detecting optic nerve damage. MRV abnormalities, particularly transverse sinus stenosis, have also gained increasing attention. Recent literature emphasizes the importance of multidisciplinary management involving neurosurgeons, neurologists, ophthalmologists, and radiologists.

Timeline

Start
2026-06-01
Primary completion
2026-12-01
Completion
2026-12-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Acetazolamide Small molecule
Comparator Topiramate Small molecule

Indications