Drugs / Xenon
Trials 31 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 12 trials | ||||||
| Phase 1 | NCT06945614 | Apr → Dec 2025 overdue | — | General Biophysics LLC | Recruiting | No outcome recorded |
| Phase 1 | NCT01043419 | Jan → Mar 2010 | sympathetic nervous system disorder | Air Liquide | Completed | No outcome recorded |
| Phase 1/22 trials | ||||||
| Phase 1/2 | NCT07435103 | Mar 2026 → Mar 2027 expected | autism | The Children's Hospital of Zhejiang University School of Medicine | Not yet recruiting | No outcome recorded |
| Phase 1/2 | NCT01545271 | May 2012 → Oct 2013 | brain hypoxia - ischemia | University Hospitals Bristol and Weston NHS Foundation Trust | Completed | No outcome recorded |
| Phase 28 trials | ||||||
| Phase 2 | NCT04696523 | Apr 2025 → Dec 2029 expected | acquired aneurysmal subarachnoid hemorrhage, brain injury, brain ischemia, cerebral infarction +1 | Turku University Hospital | Recruiting | No outcome recorded |
| Phase 2 | NCT02768727 | Apr 2016 → Dec 2019 | cognitive disorder | University of Pennsylvania | Completed | No outcome recorded |
| Phase 2 | NCT02071394 | Mar 2014 → Oct 2019 | brain hypoxia - ischemia | University Hospitals Bristol and Weston NHS Foundation Trust | Completed | No outcome recorded |
| Phase 2 | NCT02098148 | Nov 2013 → Jan 2014 | obsessive-compulsive disorder | Mclean Hospital | Withdrawn | No outcome recorded |
| Phase 2 | NCT01757106 | Dec 2012 → Jul 2013 | coronary artery disorder | Universitaire Ziekenhuizen KU Leuven | Completed | No outcome recorded |
| Phase 2 | NCT01696630 | Oct 2012 → Jul 2014 | colorectal cancer | Centre Leon Berard | Completed | No outcome recorded |
| Phase 2 | NCT01262729 | Sep 2011 → Nov 2014 | cardiac arrest | RWTH Aachen University | Terminated | No outcome recorded |
| Phase 2 | NCT01199276 | Sep 2010 → Oct 2014 | delirium | Air Liquide | Completed | No outcome recorded |
| Phase 2/32 trials | ||||||
| Phase 2/3 | NCT04432155 | Jun → Nov 2021 | panic disorder | Nobilis Therapeutics Inc. | Unknown | No outcome recorded |
| Phase 2/3 | NCT03635827 | Jun 2021 | post-traumatic stress disorder | Nobilis Therapeutics Inc. | Unknown | No outcome recorded |
| Phase 39 trials | ||||||
| Phase 3 | NCT03176186 | Mar 2026 → Apr 2029 expected | post-cardiac arrest syndrome | Invero Pharma, Inc. | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT05335109 | Jan 2022 → Jan 2024 | ischemic stroke | Negovsky Reanimatology Research Institute | Completed | No outcome recorded |
| Phase 3 | NCT02129400 | May 2014 → Jan 2015 | — | RWTH Aachen University | Terminated | No outcome recorded |
| Phase 3 | NCT01839084 | Jul 2013 → Feb 2016 | — | RWTH Aachen University | Completed | No outcome recorded |
| Phase 3 | NCT01285271 | May → Sep 2011 | coronary artery disorder | RWTH Aachen University | Completed | No outcome recorded |
| Phase 3 | NCT01294163 | Apr 2011 → Apr 2014 | coronary artery disorder, drug allergy | Air Liquide | Completed | No outcome recorded |
| Phase 3 | NCT01120405 | May 2010 → Jul 2012 | coronary artery disorder | Air Liquide | Completed | No outcome recorded |
| Phase 3 | NCT00919126 | Jun 2009 → Jan 2012 | — | Air Liquide SA | Terminated | No outcome recorded |
| Phase 3 | NCT00192959 | Mar → Dec 2004 | — | Rigshospitalet, Denmark | Completed | No outcome recorded |
| Phase 45 trials | ||||||
| Phase 4 | NCT03504033 | Apr 2018 → Sep 2019 | — | RWTH Aachen University | Withdrawn | No outcome recorded |
| Phase 4 | NCT02682758 | Feb → Mar 2016 | — | Heinrich-Heine University, Duesseldorf | Completed | No outcome recorded |
| Phase 4 | NCT01167803 | Dec 2010 → Nov 2012 | obesity disorder | Nîmes University Hospital | Completed | No outcome recorded |
| Phase 4 | NCT00937807 | Jul 2009 → Feb 2010 | — | Air Liquide | Completed | No outcome recorded |
| Phase 4 | NCT00793663 | Nov 2008 → Apr 2011 | — | RWTH Aachen University | Completed | No outcome recorded |
| Phase not applicable3 trials | ||||||
| — | NCT02774096 | Feb 2016 → Jul 2018 | aortic disorder | Beijing Anzhen Hospital | Unknown | No outcome recorded |
| — | NCT02468531 | Jan 2015 → Jul 2017 | acute lung injury | Beijing Anzhen Hospital | Unknown | No outcome recorded |
| — | NCT01404819 | Apr 2012 → Feb 2015 | — | Nîmes University Hospital | Completed | No outcome recorded |
Also used as a comparator or background therapy in 4 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 02 trials | ||||||
| Phase 0 | NCT06080100 Comparator | Nov 2023 → Jan 2026 overdue | anxiety | The S.N. Fyodorov Eye Microsurgery State Institution | Recruiting | No outcome recorded |
| Phase 0 | NCT03748446 Comparator | Dec 2019 → Sep 2026 expected | bipolar depression, major depressive disorder | Massachusetts General Hospital | Active not recruiting | No outcome recorded |
| Phase 22 trials | ||||||
| Phase 2 | NCT01948765 Comparator | Jun 2013 → Sep 2014 | coronary artery disorder | Universitaire Ziekenhuizen KU Leuven | Completed | No outcome recorded |
| Phase 2 | NCT00879892 Comparator | May 2009 → Sep 2014 | brain ischemia | Turku University Hospital | Completed | No outcome recorded |
Evidence & citations 5 cited values
Every value below carries the sentence it was read from. 36 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Xenon | “Xenon arm will be treated with xenon inhalation with endtidal concentration of 50 % in air/oxygen and with standard of care” NCT04696523 ↗34 |
| Known as | LENOXe | “Hemodynamic Stability During Carotid Endarterectomy.Comparison of LENOXe™ (Xenon 100% v/v) Versus Sevoflurane” NCT00937807 ↗1“Security under LENOXe™ (xénon 100 % v/v) anesthesia” NCT01043419 ↗ |
| Action | Inhibit | “In vitro, Xe decreases the uptake of NE in neuronal cells by the inhibition of NET.” PMID 22945969 ↗ Sep 2012 |
| Modality | Other / unclassified | “The N-methyl-d-aspartate (NMDA) receptor (NMDA-R) antagonist xenon (Xe) induces general anaesthesia” PMID 22945969 ↗ Sep 2012 |
| Route | Inhaled | “inhaled xenon” NCT00192959 ↗ |