Drugs / Iron Sulfate
last change Jun 2026 re-read 2 minutes ago

Iron Sulfate

Small molecule

Developed for
anemia · iron deficiency anemia · disorder of iron metabolism and transport · Crohn disease · deficiency anemia · diarrheal disease · disruptive behavior disorder · heavy metal poisoning
+10 more · inflammatory bowel disease · neural tube defect · perceptual disorders · pneumonia · symptomatic heart failure · visceral leishmaniasis · anemia of prematurity · chemotherapy-induced toxicity · fibromyalgia · vulvovaginal candidiasis
Investigated by
International Centre for Diarrhoeal Disease Research, Bangladesh · AMAG Pharmaceuticals, Inc. · Access to Advanced Health Institute (AAHI) · Agencia Española de Cooperación Internacional · Akzo Nobel · American University of Beirut Medical Center
+30 more · Ann & Robert H Lurie Children's Hospital of Chicago · Annamalai University · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh · Bill and Melinda Gates Foundation · Cairo University · Centers for Disease Control and Prevention · Emory University · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · Hippocration General Hospital · Hospital Clinic of Barcelona · Jerring Foundation, Sweden · Jinling Hospital, China · Johns Hopkins Bloomberg School of Public Health · Kenya Medical Research Institute · Loma Linda University · Ministry of Health, China · Nagasaki University · Oskar Foundation · Padjadjaran University · Regione Piemonte · Rennes University Hospital · Shanghai Jiao Tong University School of Medicine · The Swedish Research Council for Environment, Agricultural Sciences and Spatial Planning (FORMAS) · Umeå University · Unilever Food and Health Research Institute, The Netherlands · United States Agency for International Development (USAID) · University Hospital, Geneva · University of Turin, Italy · Wageningen University · World Health Organization

Trials 23 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT02957643 Nov 2016 → Sep 2017 deficiency anemia Hippocration General Hospital Completed No outcome recorded
Phase 24 trials
Phase 2 NCT02908581 Jun 2016 → Apr 2017 heavy metal poisoning Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh Completed No outcome recorded
Phase 2 NCT01949467 Feb 2014 → Dec 2017 hemochromatosis type 4 Rennes University Hospital Completed No outcome recorded
Phase 2 NCT00964496 Nov 2004 → Nov 2007 angiodysplasia, gastric antral vascular ectasia Shanghai Jiao Tong University School of Medicine Completed No outcome recorded
Phase 2 NCT00386074 May → Dec 2004 anemia Wageningen University Completed No outcome recorded
Phase 36 trials
Phase 3 NCT04691843 Feb 2021 → Aug 2024 iron deficiency anemia Ann & Robert H Lurie Children's Hospital of Chicago Completed No outcome recorded
Phase 3 NCT02631980 Oct 2015 → Oct 2016 anemia University Hospital, Geneva Completed No outcome recorded
Phase 3 NCT00255437 Jun 2004 → Nov 2006 anemia AMAG Pharmaceuticals, Inc. Completed No outcome recorded
Phase 3 NCT00255424 May 2004 → Aug 2006 anemia AMAG Pharmaceuticals, Inc. Completed No outcome recorded
Phase 3 NCT00255385 Apr 2002 → Apr 2004 diarrheal disease, pneumonia Johns Hopkins Bloomberg School of Public Health Completed No outcome recorded
Phase 3 NCT00109551 Oct 2001 → Jan 2006 Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Completed No outcome recorded
Phase 44 trials
Phase 4 NCT06550362 Dec 2026 → May 2027 expected iron deficiency anemia Loma Linda University Not yet recruiting No outcome recorded
Phase 4 NCT06427200 Jul 2024 → Jul 2027 expected symptomatic heart failure Cairo University Not yet recruiting No outcome recorded
Phase 4 NCT02774057 Mar 2016 → Jul 2017 inflammatory bowel disease, iron deficiency anemia American University of Beirut Medical Center Unknown No outcome recorded
Phase 4 NCT00558454 Mar 2004 → Jun 2008 anemia, disorder of iron metabolism and transport, disruptive behavior disorder, perceptual disorders Umeå University Completed No outcome recorded
Phase not applicable8 trials
NCT06875947 May 2025 → Apr 2026 overdue iron deficiency anemia, pregnancy disorder Padjadjaran University Active not recruiting No outcome recorded
NCT03073590 Jan 2016 → Jun 2017 anemia International Centre for Diarrhoeal Disease Research, Bangladesh Completed No outcome recorded
NCT01823029 Nov 2012 → Jul 2013 Crohn disease Jinling Hospital, China Completed No outcome recorded
NCT01069198 Oct 2009 → Oct 2010 visceral leishmaniasis International Centre for Diarrhoeal Disease Research, Bangladesh Completed No outcome recorded
NCT00394862 Jan → Jun 2006 neural tube defect Emory University Completed No outcome recorded
NCT01507792 Jan 2002 → Jan 2011 bronchial disorder, disorder of iron metabolism and transport, laryngeal disorder University of Turin, Italy Completed No outcome recorded
NCT00284700 Dec 1997 → May 2001 Helicobacter pylori infectious disease, iron deficiency anemia International Centre for Diarrhoeal Disease Research, Bangladesh Completed No outcome recorded
NCT00497471 Feb 1995 → Jul 1999 Plasmodium falciparum malaria, iron deficiency anemia Hospital Clinic of Barcelona Terminated No outcome recorded
Also used as a comparator or background therapy in 24 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT07577817 Background Jun → Oct 2026 expected anemia, chronic kidney disease, disorder of iron metabolism and transport Cajal Therapeutics Inc. Recruiting No outcome recorded
Phase 22 trials
Phase 2 NCT02564796 Comparator Nov 2016 → Jun 2020 anemia, congenital heart disease University of California, San Diego Terminated No outcome recorded
Phase 2 NCT01490944 Background Jan → Nov 2012 anemia Indian Council of Medical Research Unknown No outcome recorded
Phase 311 trials
Phase 3 NCT04464850 Comparator Jul 2020 → Jan 2021 iron deficiency anemia Chiang Mai University Unknown No outcome recorded
Phase 3 NCT04189367 Background Jun 2020 → Jul 2022 burning mouth syndrome Chang Gung Memorial Hospital Unknown No outcome recorded
Phase 3 NCT02278341 Background Nov 2014 → Jun 2017 anemia, end stage renal failure Astellas Pharma Europe B.V. Completed No outcome recorded
Phase 3 NCT01787526 Comparator Jun 2014 → Aug 2016 iron deficiency anemia Medical University of Graz Completed No outcome recorded
Phase 3 NCT01820052 Comparator Apr 2013 → May 2015 fibromyalgia Sanjay Gandhi Postgraduate Institute of Medical Sciences Completed No outcome recorded
Phase 44 trials
Phase 4 NCT04497012 Comparator Nov 2020 → Mar 2025 anemia of prematurity University of South Florida Unknown No outcome recorded
Phase 4 NCT04391998 Comparator May 2020 → Aug 2021 anemia Cairo University Unknown No outcome recorded
Phase 4 NCT03542825 Comparator Jan → Sep 2018 iron deficiency anemia South Valley University Completed No outcome recorded
Phase 4 NCT02487719 Comparator Jun 2015 → Jun 2016 iron deficiency anemia, pregnancy disorder University of Zurich Unknown No outcome recorded
Phase not applicable6 trials
NCT05678647 Comparator Jan 2023 → Mar 2026 Uppsala University Hospital Completed No outcome recorded
NCT04101461 Comparator Oct 2019 → Apr 2022 anemia Assiut University Completed No outcome recorded
NCT02949765 Comparator Dec 2015 → Jun 2017 celiac disease, disorder of iron metabolism and transport Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico Unknown No outcome recorded
NCT01265680 Background Feb → Nov 2012 Cardiochirurgia E.H. Completed No outcome recorded
NCT00269542 Background Feb 2002 → Mar 2003 diarrheal disease, pneumonia Society for Applied Studies Completed No outcome recorded

Evidence & citations 16 cited values

Every value below carries the sentence it was read from. 51 sources stand behind the page.

FieldValueCited text
Known as Iron Sulfate “Patients were randomized in a 2:1 ratio to either intravenous iron isomaltoside or oral iron sulfate.” PMID 26927900 Apr 2016
7

Iron Sulfate will be given in liquid form via nasal or oral gastric tube with feeds.” NCT04497012

NCT04691843

NCT06550362

NCT02487719

NCT02774057

NCT02949765

NCT05678647

Known as Electrolytic Iron ClinicalTrials.gov intervention name — accepted as the source's own label NCT00386074
Known as Ferrous fumarate component of lo minastrin fe ChEMBL registry synonym — accepted as the source's own label CHEMBL1200640
Known as Ferrous fumarate component of minastrin 24 fe ChEMBL registry synonym — accepted as the source's own label CHEMBL1200640
Known as Ferrous fumarate component of norquest fe ChEMBL registry synonym — accepted as the source's own label CHEMBL1200640
Known as ferrum metallicum ClinicalTrials.gov intervention name — accepted as the source's own label NCT00895453
Known as Fersaday ChEMBL registry synonym — accepted as the source's own label CHEMBL1200640
Known as Fersamal ChEMBL registry synonym — accepted as the source's own label CHEMBL1200640
Known as Fumafer “All patients will receive a tablet of 66mg of iron, in the form of iron fumarate (Fumafer®) with 50 ml water.” NCT01949467
Known as iron “the intervention will consist of the twice weekly provision of iron/folate supplements to female workers, and the enhanced BCC program, as described above.” NCT03073590
29

“Nutritional supplement: vitamin B12, folic acid, iron, zinc, vitamin B complex depending on the hematic deficiency, for 12 weeks” NCT04189367

“80.000 UI of Human Recombinant Erythropoietin and intravenous iron at time of arrival at the hospital” NCT01265680

“different levels of folic acid, Vitamin B12, iron and zinc” NCT00394862

NCT00255424

NCT02957643

NCT04101461

NCT02631980

NCT02908581

NCT06427200

NCT00284700

NCT00109551

NCT01490944

NCT01069198

NCT07577817

NCT00755755

NCT00255385

NCT00497471

NCT00558454

NCT06875947

NCT00964496

NCT02278341

NCT00269542

NCT04391998

NCT01820052

NCT00255437

NCT01823029

NCT02564796

NCT04497012

NCT01553123

Known as iron (II)fumarate “176 healthy male and female blood donors with iron deficiency (ferritin ≤30 ng/mL) were randomized to either a single dose of IV ferric carboxymaltose (1000 mg, n = 86) or oral...” PMID 30981629 Mar 2019
Known as iron fumarate “1 tablet, three times a day, of iron fumarate will be prescribed for 24 weeks of study period.” NCT04464850
2

“oral iron supplementation (10 g iron fumarate, 100 capsules, n = 90).” PMID 32380660 May 2020

NCT01949467

Known as iron sulphate “Patients will receive iron sulphate, 500 mg, BID, plus orange juice, for 6 weeks.” NCT01414374
5

Iron Sulphate 150 mg once daily” NCT03542825

NCT01145638

NCT01507792

NCT01017614

NCT01102413

Modality Other / unclassified “micronutrients (especially of zinc and iron)” PMID 20730057 Aug 2010
Modality Small molecule CHEMBL1200640
Route Oral “children consuming MN milk” PMID 20730057 Aug 2010