Drugs / Mebendazole
Mebendazole
also known as
MBZ · Emverm · MBD · Mebendazol · Mebendazole polymorph c · Mebendazolum · Mebenvet · NSC-184849 · +7 more
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | VERMOX | — | 1974-06-28 | fda.gov ↗ |
Trials 21
News releases announcing trial results or a regulatory action · 1
| Date | Issuer | Release |
|---|---|---|
| 2019-04-09 | Janssen Research & Development, LLC | Regulatory New Pediatric Formulation of Janssen’s Treatment for Intestinal Worms Achieves World Health Organization Prequalification jnj.com ↗
Raritan, N.J., April 9, 2019 – Janssen Pharmaceutica N.V., one of the Janssen Pharmaceutical Companies of Johnson & Johnson, today announced that the World Health Organization (WHO) has prequalified the company’s new pediatric formulation of a treatment for intestinal worms. |
All press releases naming this drug 4 releases
| Date | Issuer | Release |
|---|---|---|
| 2024-01-30 | Janssen Research & Development, LLC | Johnson & Johnson Announces Intention to Extend Longstanding VERMOX® Donation Program through 2030 to Tackle Intestinal Worms and Help Children in Marginalized Communities Thrive jnj.com ↗ |
| 2019-04-09 | Janssen Research & Development, LLC | New Pediatric Formulation of Janssen’s Treatment for Intestinal Worms Achieves World Health Organization Prequalification jnj.com ↗ |
| 2016-04-13 | Impax Laboratories, LLC | Impax Announces Availability of EMVERM™ (mebendazole) Chewable Tablets, 100 mg amneal.com ↗ |
| 2016-01-15 | Impax Laboratories, LLC | Impax Receives Approval of EMVERM™ (mebendazole) Chewable Tablets, 100 mg amneal.com ↗ |
Evidence & citations 19 cited values
Every value below carries the sentence it was read from. 35 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | mebendazole | “Participants were randomly assigned to one of three treatment arms. On the first and third days, all participants got albendazole 400 mg, and on the second day, albendazole...” PMID 38563751 ↗ Apr 202430“Nitazoxanide, Chloroquine, Albendazole, Ivermectin, Mebendazole, Metronidazole, Praziquantel, Levamisole” NCT02366884 ↗ “Albendazole treatment, 400 mg x 2/d (or mebendazole if adverse effects)” NCT02876146 ↗ “Oral Mebendazole 100mg uid, for study duration.” NCT02201381 ↗ |
| Known as | Emverm | ChEMBL registry synonym — accepted as the source's own label CHEMBL685 ↗ |
| Known as | MBD | “This randomised, controlled, double-blinded clinical study investigates the safety and efficacy of albendazole (ALB), mebendazole (MBD) and ivermectin (IVM) separately, and ALB...” NCT01050452 ↗ |
| Known as | MBZ | “Purpose: To assess the efficacy of three proposed anthelminthic combination regimens for the treatment of strongyloidiasis using real-time polymerase chain reaction (real-time...” PMID 41364144 ↗ Dec 20252“A randomised clinical trial was conducted in Kabale District, southwestern Uganda, to compare the efficacies of single and double doses of a combination of 400mg albendazole...” PMID 21885077 ↗ Aug 2011 “The primary objective is: (1) to monitor the efficacy a single dose 500 mg of mebendazole (MBZ) against Soil-Transmitted Helminths (STH) infections by means of Faecal Egg...” NCT01379326 ↗ |
| Known as | Mebendazol | ChEMBL registry synonym — accepted as the source's own label CHEMBL685 ↗ |
| Known as | Mebendazole polymorph c | ChEMBL registry synonym — accepted as the source's own label CHEMBL685 ↗ |
| Known as | Mebendazolum | ChEMBL registry synonym — accepted as the source's own label CHEMBL685 ↗ |
| Known as | Mebenvet | ChEMBL registry synonym — accepted as the source's own label CHEMBL685 ↗ |
| Known as | NSC-184849 | ChEMBL registry synonym — accepted as the source's own label CHEMBL685 ↗ |
| Known as | Ovitelmin | ChEMBL registry synonym — accepted as the source's own label CHEMBL685 ↗ |
| Known as | Pantelmin | ChEMBL registry synonym — accepted as the source's own label CHEMBL685 ↗ |
| Known as | R 17,635 | ChEMBL registry synonym — accepted as the source's own label CHEMBL685 ↗ |
| Known as | Telmintic | ChEMBL registry synonym — accepted as the source's own label CHEMBL685 ↗ |
| Known as | Vermicidin | ChEMBL registry synonym — accepted as the source's own label CHEMBL685 ↗ |
| Known as | Vermox | ChEMBL registry synonym — accepted as the source's own label CHEMBL685 ↗ |
| Known as | Zhihuanqing | ChEMBL registry synonym — accepted as the source's own label CHEMBL685 ↗ |
| Action | Inhibit | “Mebendazole has broad range of action by not only inhibiting angiogenesis and pro-survival pathways of MAPK” NCT04443049 ↗ |
| Modality | Small molecule | “A Randomized Controlled Clinical Trial (RCT) cohort study, to evaluate the efficacy and safety of three benzimidazole derivates drug (Albendazole, Mebendazole, Albendazole...” NCT04326868 ↗ |
| Route | Oral | “route= oral use.” NCT01173562 ↗ |