Drugs / Tocopherol
Tocopherol
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | INFUVITE PEDIATRIC (PHARMACY BULK PACKAGE) | — | 2001-02-21 | fda.gov ↗ |
Trials 14
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT03723291 | Sep 2019 → Dec 2021 | — | University College, London | Completed | No outcome recorded |
| Phase 25 trials · 1 missed | ||||||
| Phase 2 | NCT06912763 | Aug 2025 → Mar 2031 expected | head and neck cancer, lymphedema | M.D. Anderson Cancer Center | Recruiting | No outcome recorded |
| Phase 2 | NCT06494111 | Feb 2025 → May 2029 expected | lymphedema | M.D. Anderson Cancer Center | Recruiting | No outcome recorded |
| Phase 2 | NCT05795647 | Feb 2024 → Apr 2027 expected | osteonecrosis of the jaw | University Hospital, Limoges | Recruiting | No outcome recorded |
| Phase 2 | NCT00162526 | Dec 2005 → ? | chemotherapy-induced oral mucositis | Hadassah Medical Organization | Withdrawn | No outcome recorded |
| Phase 2 | NCT00002586 | Jan 1993 → Dec 2005 | lung cancer, poisoning | University of Colorado, Denver | Completed | Missed primary |
| Phase 35 trials | ||||||
| Phase 3 | NCT06055257 | Jan 2025 → Dec 2027 expected | osteoradionecrosis of the mandible | Sunnybrook Health Sciences Centre | Recruiting | No outcome recorded |
| Phase 3 | NCT05350124 | Nov 2022 → Dec 2023 | end stage renal failure, restless legs syndrome | King Abdulaziz University | Unknown | No outcome recorded |
| Phase 3 | NCT05016349 | Aug → Oct 2021 | female breast carcinoma | Mahmoud Ramadan mohamed Elkazzaz | Unknown | No outcome recorded |
| Phase 3 | NCT03040778 | Apr 2018 → May 2026 overdue | osteonecrosis of the jaw | University of Washington | Active not recruiting | No outcome recorded |
| Phase 3 | NCT00119119 | Feb 2002 → Dec 2006 | chronic hepatitis C virus infection, fibrotic liver disease | French National Agency for Research on AIDS and Viral Hepatitis | Terminated | No outcome recorded |
| Phase 43 trials | ||||||
| Phase 4 | NCT04360889 | Sep 2019 → Aug 2022 | lymphedema | Ryazan State Medical University | Completed | No outcome recorded |
| Phase 4 | NCT02368457 | Feb 2016 | osteoradionecrosis | Hospital Vall d'Hebron | Completed | No outcome recorded |
| Phase 4 | NCT03228238 | Sep 2014 → Jun 2024 | Prinzmetal angina | Seoul National University Hospital | Terminated | No outcome recorded Stop: Enrollment |
| Comparator or background therapy4 trials | ||||||
| Phase 2 | NCT01822405 Comparator | Jul 2010 → Jul 2013 | — | Hospital Universitario de Canarias | Unknown | No outcome recorded |
| Phase 4 | NCT05813249 Comparator | Feb 2023 → Feb 2024 | NAFLD1 | Zagazig University | Completed | No outcome recorded |
| — | NCT06409546 Comparator | Apr 2020 → Dec 2023 | osteonecrosis of the jaw | University of Catania | Completed | No outcome recorded |
| — | NCT00893724 Comparator | Jun 2009 → Aug 2011 | diabetic macular edema, wet macular degeneration | Mid-Atlantic Retina Consultations, Inc. | Unknown | No outcome recorded |
Evidence & citations 4 cited values
Every value below carries the sentence it was read from. 18 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Tocopherol | “13-Cis Retinoic Acid (50 mg/day) Tocopherol (800 mg/day)” NCT00002586 ↗17“Ascorbic acid Tablet 1g and Tocopherol Capsule 400IU” NCT03228238 ↗ “800 IU tocopherol (400 IU morning and night)” NCT06055257 ↗ |
| Known as | alfa-tocopherol | “Pentoxifylline 800 mg/day (400 mg/12hours) + Vitamin E (alfa-tocopherol) 1000 mg/day,oral during 6 months” NCT01822405 ↗1“Vitamin E (alfa-tocopherol) 1000 UI/day, oral (1cp 400UI twice a day + 1cp200UI once a day)” NCT02368457 ↗ |
| Known as | Vitamin E | “Pentoxifylline 800 mg/day (400 mg/12hours) + Vitamin E (alfa-tocopherol) 1000 mg/day,oral during 6 months” NCT01822405 ↗3“Vitamin E (alfa-tocopherol) 1000 UI/day, oral (1cp 400UI twice a day + 1cp200UI once a day)” NCT02368457 ↗ “Vitamin C and Vitamin E : Ascorbic acid Tablet 1g / Tocopherol Capsule 400IU” NCT03228238 ↗ “Tocopherol (Vitamin E) has antioxidant properties.” NCT03723291 ↗ |
| Route | Oral | “Pentoxifylline 800 mg/day (400 mg/12hours) + Vitamin E (alfa-tocopherol) 1000 mg/day,oral during 6 months” NCT01822405 ↗ |