drugset / Trial / NCT00002535
Indomethacin Plus Biological Therapy in Treating Patients With Advanced Melanoma
Treatment
Summary
RATIONALE: Biological therapies use different ways to stimulate the immune system and stop tumor cells from growing. Combining biological therapies with indomethacin and cyclophosphamide may kill more tumor cells. PURPOSE: Phase II trial to compare the effectiveness of indomethacin and biological therapy with or without cyclophosphamide in treating patients who have advanced melanoma that has not responded to previous therapy.
Timeline
- Start
- 1993-07
- Primary completion
- —
- Completion
- 2004-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cyclophosphamide | Other / unclassified | — | — |
| Subject | Indomethacin | Small molecule | — | — |
| Subject | Tumor Infiltrating Lymphocytes | Cell therapy | — | — |
| Subject | aldesleukin | Protein / enzyme biologic | — | — |
| Subject | lymphokine-activated killer cells | Cell therapy | — | — |