drugset / Trial / NCT00003101
Combination Chemotherapy and Bone Marrow Transplantation or Peripheral Stem Cell Transplantation in Treating Patients With Oligodendroglioma
Phase 2
Completed
60 enrolled
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI) · collab
Treatment
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and combining chemotherapy with autologous bone marrow transplantation or peripheral stem cell transplantation may allow doctors to give higher doses of chemotherapy drugs and kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy plus bone marrow transplantation or peripheral stem cell transplantation in treating patients who have oligodendroglioma.
Timeline
- Start
- 1997-08
- Primary completion
- 2002-01
- Completion
- 2002-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Busulfan | Small molecule | — | Intravenous |
| Subject | Lomustine | Small molecule | — | Oral |
| Subject | Thiotepa | Other / unclassified | — | Intravenous |
| Subject | Vincristine | Small molecule | — | Intravenous |
| Subject | procarbazine | Small molecule | — | — |
| Background | filgrastim | Protein / enzyme biologic | — | Subcutaneous |