drugset / Trial / NCT00003603
Chemotherapy Plus Steroid Therapy in Treating Patients With Multiple Myeloma
RandomizedTreatment
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. Steroids, such as dexamethasone or prednisolone, may help relieve some of the side effects of chemotherapy. It is not yet known which regimen of chemotherapy plus steroid therapy is more effective in treating patients with multiple myeloma. PURPOSE: Randomized phase III trial to compare the effectiveness of two different regimens of chemotherapy plus steroid therapy in treating patients with multiple myeloma that has recurred for the first time.
Timeline
- Start
- 1998-03
- Primary completion
- —
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexamethasone | Small molecule | — | Oral |
| Subject | Idarubicin | Small molecule | — | Oral |
| Subject | Lomustine | Small molecule | — | Oral |
| Subject | Melphalan | Small molecule | — | Oral |
| Subject | Prednisolone | Other / unclassified | — | Oral |
| Background | Cyclophosphamide | Other / unclassified | — | Oral |