drugset / Trial / NCT00004224
Combination Chemotherapy Followed by Radiation Therapy in Treating Children With Localized Ependymoma
Phase 2
Completed
65 enrolled
International Society of Pediatric Oncology
Children's Cancer and Leukaemia Group · collabItalian Association for Pediatric Hematology Oncology · collab
Treatment
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining more than one drug and combining chemotherapy with radiation therapy may kill more tumor cells. PURPOSE: This phase II trial is studying combination chemotherapy and radiation therapy to see how well they work in treating children with localized ependymoma.
Timeline
- Start
- 1999-01
- Primary completion
- —
- Completion
- 2008-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cyclophosphamide | Other / unclassified | — | Intravenous |
| Subject | Etoposide | Small molecule | — | Intravenous |
| Subject | Vincristine | Small molecule | — | Intravenous |