drugset / Trial / NCT00048802
Treatment and Outcome of Early Onset Bipolar Disorder
RandomizedParallel-groupDouble-blindTreatment
Summary
This study will compare the effectiveness in the maintenance of continuing adjunctive atypical antipsychotic medication compared to traditional mood stabilizer(s) alone in the maintenance treatment of adolescents with bipolar disorder.
Timeline
- Start
- 2002-08
- Primary completion
- 2006-08
- Completion
- 2006-08
Publications
- Background Kafantaris V, Coletti DJ, Dicker R, Padula G, Kane JM. Adjunctive antipsychotic treatment of adolescents with bipolar psychosis. J Am Acad Child Adolesc Psychiatry. 2001 Dec;40(12):1448-56. doi: 10.1097/00004583-200112000-00016.
- Background Kafantaris V. Treatment of bipolar disorder in children and adolescents. J Am Acad Child Adolesc Psychiatry. 1995 Jun;34(6):732-41. doi: 10.1097/00004583-199506000-00013.
- Background Kafantaris V, Coletti D, Dicker R, Padula G, Kane JM. Lithium treatment of acute mania in adolescents: a large open trial. J Am Acad Child Adolesc Psychiatry. 2003 Sep;42(9):1038-45. doi: 10.1097/01.CHI.0000070247.24125.24.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Aripriprazole | Unknown | — | — |
| Subject | Olanzapine | Small molecule | — | — |
| Subject | Quetiapine | Small molecule | — | — |
| Subject | Risperidone | Other / unclassified | — | — |
| Subject | Ziprasidone | Small molecule | — | — |
| Background | Divalproex Sodium | Small molecule | — | — |
| Background | Lithium | Unknown | — | — |