drugset / Trial / NCT00635349
A Comparative Study of Tramadol Hydrochloride Plus Acetaminophen Tablets Maintenance Versus Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Maintenance in Participants With Knee Osteoarthritis
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to compare the effectiveness of tramadol hydrochloride 37.5 milligram (mg) plus acetaminophen 325 mg maintenance with that of non-steroidal anti-inflammatory drugs (NSAIDs) maintenance in participants with knee osteoarthritis (a progressive and degenerative joint disease, in which the joints become painful and stiff) whose pain was relieved after the add-on treatment of tramadol hydrochloride to NSAIDs.
Timeline
- Start
- 2007-05
- Primary completion
- 2009-04
- Completion
- 2009-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Aceclofenac | Small molecule | 100 mg | — |
| Subject | Acetaminophen | Small molecule | 325 mg | — |
| Subject | Meloxicam | Small molecule | 7.5 mg | — |
| Subject | Meloxicam | Small molecule | 15 mg | — |
| Subject | Tramadol | Other / unclassified | 37.5 mg | — |