drugset / Trial / NCT00664846
Standard Medical Management in Secondary Prevention of Ischemic Stroke in China
RandomizedParallel-groupOpen-labelPrevention
Summary
The purposes of the study are to analyse the cross-section data of secondary stroke prevention in China and to carry out a standard medical management including medicine and interactive education program,and to evaluate the efficacy and safety of the standard medical management in secondary stroke prevention.
Timeline
- Start
- 2008-04
- Primary completion
- 2010-12
- Completion
- 2011-04
Publications
- Cao Y, Zhang M, Zhou L, Yao M, Peng B, Zhu Y, Ni J, Cui L. Consecutive Slides on Axial View Is More Effective Than Transversal Diameter to Differentiate Mechanisms of Single Subcortical Infarctions in the Lenticulostriate Artery Territory. Front Neurol. 2019 Apr 9;10:336. doi: 10.3389/fneur.2019.00336. eCollection 2019.
- Yao M, Ni J, Zhou L, Peng B, Zhu Y, Cui L; SMART investigators. Elevated Fasting Blood Glucose Is Predictive of Poor Outcome in Non-Diabetic Stroke Patients: A Sub-Group Analysis of SMART. PLoS One. 2016 Aug 5;11(8):e0160674. doi: 10.1371/journal.pone.0160674. eCollection 2016.
- Ni J, Yao M, Zhou L, Zhu Y, Peng B, Cui L; SMART Investigators. A guideline-based program may improve the outcome of stroke among illiterate patients. Int J Stroke. 2016 Apr;11(3):332-7. doi: 10.1177/1747493015626151. Epub 2016 Jan 18.
- Peng B, Ni J, Anderson CS, Zhu Y, Wang Y, Pu C, Wu J, Wang J, Zhou L, Yao M, He J, Shan G, Gao S, Xu W, Cui L; SMART Investigators. Implementation of a structured guideline-based program for the secondary prevention of ischemic stroke in China. Stroke. 2014 Feb;45(2):515-9. doi: 10.1161/STROKEAHA.113.001424. Epub 2014 Jan 2.
- Peng B, Zhu Y, Cui L, Ni J, Xu W, Zhou L, Yao M, Chen L, Wang J, Wang Y, Pu C; SMART Study Group. Standard medical management in secondary prevention of ischemic stroke in China (SMART). Int J Stroke. 2011 Oct;6(5):461-5. doi: 10.1111/j.1747-4949.2011.00648.x.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Acarbose | Unknown | 50 mg | — |
| Background | Amlodipine | Other / unclassified | 5 mg | — |
| Background | Aspirin | Small molecule | 75 mg | — |
| Background | Aspirin | Small molecule | 150 mg | — |
| Background | Atorvastatin | Small molecule | 20 mg | — |
| Background | Benazepril | Unknown | 10 mg | — |
| Background | Clopidogrel | Small molecule | 75 mg | — |
| Background | Glipizide | Small molecule | 5 mg | — |
| Background | Indapamide | Small molecule | 2.5 mg | — |
| Background | Metformin | Small molecule | — | — |
| Background | Nifedipine | Other / unclassified | 30 mg | — |
| Background | Simvastatin | Small molecule | 20 mg | — |
| Background | Valsartan | Unknown | 80 mg | — |