drugset / Trial / NCT00734123
Early Detection of Atherosclerosis: a Randomized Trial in the Primary Prevention of Cardiovascular Diseases.
RandomizedParallel-groupOpen-labelPrevention
Summary
The incidence of cardiovascular diseases is still high and further efforts should be done in primary prevention. The main objective is to quantify the burden of subclinical atherosclerosis using non-invasive techniques,and to study the impact of this assessment and consequent treatment in the progression of atherosclerosis and in the incidence of cardiovascular diseases.
Timeline
- Start
- 2008-04
- Primary completion
- 2009-04
- Completion
- 2013-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Aspirin | Small molecule | 100 mg | — |
| Subject | Atorvastatin | Small molecule | 20 mg | — |
| Subject | Atorvastatin | Small molecule | 40 mg | — |
| Subject | Clopidogrel | Small molecule | 75 mg | — |
| Subject | Enalapril | Other / unclassified | 10 mg | — |
| Subject | Simvastatin | Small molecule | 10 mg | — |
| Subject | Simvastatin | Small molecule | 40 mg | — |
| Background | Rimonabant | Small molecule | — | — |