drugset / Trial / NCT00815022

Influence of Anesthetic Temperature on Cephalad Sensory Blockade With Spinal Anesthesia

NCT00815022 ↗

Completed 400 enrolled Nanjing Medical University
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Several factors influence the extension of anesthetic mixture during spinal anesthesia including anesthetic gravity, body position, drug volume, and drug-delivering velocity. However, the effect of temperature of anesthetic mixture on the cephalad sensory blockade is hitherto unknown. The investigators hypothesized that different temperatures of the anesthetic mixture had different velocity of extension after spinal anesthesia. In addition, previous studies suggest that parturients have relative higher sensitivity to temperature. Herein the investigators proposed that the temperature of anesthetic mixture had more extensive effect on the cephalad sensory blockade with spinal anesthesia for cesarean delivery.

Timeline

Start
2008-12
Primary completion
2012-11
Completion
2012-12

Drugs

EvaluationDrugModalityDoseRoute
Background Bupivacaine Other / unclassified 12 mg Intrathecal
Background Fentanyl Other / unclassified 10 ug Intrathecal
Background Morphine Other / unclassified 200 ug Intrathecal

Indications

No indication recorded.