drugset / Trial / NCT01077752

Local Anesthetic Continuous Preperitoneal Infiltration and Wound Hyperalgesia

NCT01077752

Phase 3 Completed 95 enrolled Assistance Publique - Hôpitaux de Paris
RandomizedParallel-groupTriple-blindTreatment

Summary

In this multicenter, randomised, placebo-controlled, double-blind trial, hyperalgesia area around the scarce following colorectal laparoscopic surgery (piece removal) will be assessed in 3 groups of patients : group 1: continuous ropivacaine preperitoneal infusion, group 2 : intravenous lidocaine infusion, or group 3 : control group without local anesthetics. All patients will receive parenteral analgesia combining acetaminophen and morphine.

Timeline

Start
2010-02
Primary completion
2012-06
Completion
2013-02

Drugs

EvaluationDrugModalityDoseRoute
Comparator Lidocaine Other / unclassified 60 mg Intravenous
Subject Ropivacaine Other / unclassified 20 mg Other
Background Acetaminophen Small molecule Other
Background Morphine Other / unclassified Other

Indications