"Volatile Anesthetic Protection Of Renal Transplants: VAPOR-1-trail

Completed 120 enrolled University Medical Center Groningen

RandomizedParallel-groupSingle-blindPrevention

Summary

To compare the renal protective properties of two currently used anaesthetic techniques - a sevoflurane-remifentanil/sufentanil combination with a propofol-remifentanil/sufentanil combination for anaesthesia in patients undergoing living donor kidney donation/transplantation.

Timeline

Start: 2010-09
Primary completion: 2012-10
Completion: 2012-10

Publications

Nieuwenhuijs-Moeke GJ, Nieuwenhuijs VB, Seelen MAJ, Berger SP, van den Heuvel MC, Burgerhof JGM, Ottens PJ, Ploeg RJ, Leuvenink HGD, Struys MMRF. Propofol-based anaesthesia versus sevoflurane-based anaesthesia for living donor kidney transplantation: results of the VAPOR-1 randomized controlled trial. Br J Anaesth. 2017 May 1;118(5):720-732. doi: 10.1093/bja/aex057.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Propofol	Small molecule	—	—
Comparator	Sevoflurane	Other / unclassified	—	—
Comparator	Remifentanil	Small molecule	—	—
Comparator	Sufentanil	Other / unclassified	—	—

Indications

No indication recorded.